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THYROTROPIN-RELEASING HORMONE
Descriptors Found:
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DeCS
Descriptor
English
:
Thyrotropin-Releasing Hormone
Descriptor
Spanish
:
Hormona Liberadora de Tirotropina
Descriptor
Portuguese
:
Hormônio Liberador de Tireotropina
Synonyms
English
:
Prolactin-Releasing Hormone
Protirelin
Thyroliberin
Tree Number:
D06.472.699.327.740.880
D12.644.400.400.740.880
D12.644.456.837
D12.644.548.365.740.880
D12.776.641.650.405.740.880
D12.776.641.650.810
Definition
English
:
A tripeptide that stimulates the release of
THYROTROPIN
and
PROLACTIN
. It is synthesized by the
neurons
in the PARAVENTRICULAR NUCLEUS of the
HYPOTHALAMUS
. After being released into the pituitary portal circulation, TRH (was called TRF) stimulates the release of TSH and PRL from the ANTERIOR
PITUITARY GLAND.
Indexing Annotation
English
:
DF: TRH
Pharmacological Action:
Hormones
See Related
English
:
Receptors, Thyrotropin-Releasing Hormone
History Note
English
:
2006(1968)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
30447
Unique Identifier:
D013973
Occurrence in VHL
:
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